Alendronic Acid
Uses of Alendronic Acid
Salbutamol/Albuterol is commonly used in the treatment of Asthma and Chronic Obstructive Pulmonary Disease (COPD).
How Alendronic Acid Works
Salbutamol activates the enzyme that stimulates the production of cAMP. It leads to the activation of protein kinase A, which lowers intracellular ionic Ca concentration and inhibits phosphorylation of myosin. This relaxes the smooth muscle in the airways.
Side Effects of Alendronic Acid
Abdominal pain, Dyspepsia, Diarrhea, Constipation, Oesophagitis, Oesophageal erosion/ulceration, Oesophageal stricture, Peptic ulceration, Osteonecrosis of the jaw, Bone/Joint/Muscle pain, Femoral fracture, Hypocalcemia, Steven Johnson syndrome, Toxic epidermal necrolysis
Warnings
Kidney Safe If Prescribed
Do not require dose adjustment for patients with a glomerular filtration rate (GFR) greater than 35 ml/min. However, it is not recommended for patients with impaired renal function if the GFR is less than 35 ml/min, as there is no data of this.
Alcohol Safe
Alendronic Acid has no interaction with alcohol.
Pregnancy Not Safe
There are no adequate data from the use of Alendronic Acid in pregnant women. Animal studies have shown reproductive toxicity which caused dystocia related to hypocalcemia in rats. Alendronic Acid should not be used during pregnancy
Driving Generally Safe
Alendronic Acid usually does not affect the ability to drive. Do not drive unless you are feeling well..
Liver Safe If Prescribed
No dose adjustment is necessary.
Lactation Limited Data
It is not known whether Alendronic Acid are excreted in human milk. A risk to the newborns/infants cannot be excluded. Alendronic Acid not be used during breast-feeding.