Amlodipine + Telmisartan
Uses of Amlodipine + Telmisartan
The combination of Amlodipine and Telmisartan belongs to the class of antihypertensive medications and is indicated for the treatment of hypertension.
How Amlodipine + Telmisartan Works
Amlodipine, a calcium channel blocker, inhibits the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance. Telmisartan, an angiotensin II receptor blocker (ARB), blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II, resulting in further vasodilation and lowered blood pressure. The combination of Amlodipine and Telmisartan provides a synergistic antihypertensive effect by targeting different pathways in blood pressure regulation.
Side Effects of Amlodipine + Telmisartan
Dizziness, Headache, Peripheral Edema, Flushing, Cough, and Hypotension.
Warnings
Kidney Use With Care
Amlodipine + Telmisartan should be used with caution in patients with kidney problems (such as kidney transplant, narrowing of renal arteries). Therefore, consult your doctor before taking it.
Alcohol Not Advisable
Avoid consumption of alcohol while taking Amlodipine + Telmisartan as it might make you feel dizzier and drowsier.
Pregnancy Not Safe
Amlodipine + Telmisartan is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking Amlodipine + Telmisartan if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with Amlodipine + Telmisartan, stop taking it and consult your doctor immediately.
Driving Not advisable
Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking Amlodipine + Telmisartan.
Liver Use With Care
Amlodipine + Telmisartan is not recommended for use in patients with severe liver impairment (such as cholestasis, jaundice, and biliary obstruction). It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it.
Lactation Not Advisable
Amlodipine + Telmisartanis not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
