Candesartan + Hydrochlorothiazide

Uses of Candesartan + Hydrochlorothiazide

This combination medication is indicated for the management of hypertension, combining the antihypertensive effects of candesartan, an angiotensin II receptor blocker (ARB), with the diuretic action of hydrochlorothiazide.

How Candesartan + Hydrochlorothiazide Works

Candesartan blocks the action of angiotensin II, leading to vasodilation and reduced blood pressure. Hydrochlorothiazide enhances the antihypertensive effect by promoting diuresis, reducing blood volume and thus lowering blood pressure.

Side Effects of Candesartan + Hydrochlorothiazide

Common side effects may include dizziness, hypotension, electrolyte disturbances, and renal impairment.

Warnings

Kidney Use With Care

Use with care in individuals with impaired renal function. Regular monitoring is recommended for renal function.

Alcohol Limited Data

Limited data are available regarding the interaction of this medication with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.

Pregnancy Limited Data

There is limited data on the safety of this medication during pregnancy. Consultation with a healthcare provider is recommended to assess potential risks and benefits.

Driving Use With Care

Caution is advised while driving or operating machinery, as this medication may cause dizziness or drowsiness. It is essential to assess individual response before engaging in activities that require alertness.

Liver Limited Data

Limited data are available on the effects of this medication on liver function. Caution is advised, especially for individuals with liver conditions. Consultation with a healthcare professional is recommended.

Lactation Limited Data

Limited data are available regarding the safety of this medication during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).