Chlorpheniramine Maleate
Uses of Chlorpheniramine Maleate
Chlorpheniramine Maleate is commonly used to treat Allergic Conditions, Allergic Conjunctivitis, Allergic Eye Disease, Eye Irritation, Nasal Congestion Blocked Nose,
How Chlorpheniramine Maleate Works
Chlorpheniramine Maleate is an antihistamine which works by blocking histamine from H1-receptor in the gastrointestinal, respiratory tract and blood vessels, thus relieving allergic reactions in the body.
Side Effects of Chlorpheniramine Maleate
Sedation, Dizziness, Blurred vision, Nausea, Vomiting, Stomach pain, Loss of appetite, Light sensitivity, Low blood pressure
Warnings
Kidney Safe If Prescribed
No dosage adjustment is needed for people with renal impairment despite it being excreted via urine.
Alcohol Not Advisable
Chlorpheniramine Maleate and alcohol consumption may worsen the effects on the central nervous system as their adverse reactions may be compounded.
Pregnancy Not Safe
There are mixed and inadequate data to conclude the safety profile of ChlorChlorpheniramine Maleate in pregnant women. It may be safe to use in the first and second trimester but may increase the risk of premature neonates if used in the third trimester.
Driving Not advisable
It is not advisable to drive when taking Chlorpheniramine Maleate due to its potential side effects such as drowsiness and dizziness which can affect the ability to drive and concentrate.
Liver Safe If Prescribed
Although no dosage adjustment is indicated by the manufacturer labelling, precautionary measure with dosage adjustment may be needed in moderate to severe hepatic impaired patient due to Chlorpheniramine Maleate being metabolised by the liver.
Lactation Safe If Prescribed
Chlorpheniramine Maleate is present in small quantity in human breastmilk and can cause drowsiness on the infant. Close monitoring is required if using Chlorpheniramine Maleate during breastfeeding or using second generation of anti-histamine.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
