Clobetasol
Uses of Clobetasol
Clobetasol is commonly used in the treatment of allergic skin conditions, dermatitis, eczema, psoriasis, and skin disorders
How Clobetasol Works
Clobetasol is a corticosteroid which has anti-inflammatory property. It binds to glucocorticoid receptors and reduces the formation, activity, and release of prostaglandins, leukotrienes, and other inflammatory mediators.
Side Effects of Clobetasol
Headache, Skin irritation, Numbness of fingers, Burning sensation, Erythema, Skin atrophy, Bulging fontanelles, Bilateral papilloedema, Folliculitis
Warnings
Kidney Safe If Prescribed
Clobetasol is safe to be used in patients with kidney impairment.
Alcohol Safe
There is no known interaction of Clobetasol with alcohol.
Pregnancy Not Safe
Clobetasol may be unsafe to use during pregnancy. Animal reproduction studies have shown adverse effects on the fetus. However, there are limited well-controlled human studies. The benefits from the use of Clobetasol in pregnant women may be acceptable despite the risk. Please consult your doctor.
Driving Generally Safe
Clobetasol usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
Clobetasol is generally safe for patients with liver disease.
Lactation Limited Data
Clobetasol is probably unsafe to use during lactation. Animals studies showed Clobetasol is excreted in the milk of rats. Limited human data suggests that Clobetasol does not represent a significant risk to the baby.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
