Cyclopentolate
Uses of Cyclopentolate
Cyclopentolate is used before an eye surgery or eye examination. It helps to dilate the pupils.
How Cyclopentolate Works
Cyclopentolate is an antimuscarinic agent. It reversibly blocks the action of acetylcholine leading to relaxation of iris sphincter muscle producing pupil dilation. It also paralyzes the ciliary muscle of the lens causing cycloplegia.
Side Effects of Cyclopentolate
Burning & Irritation In The Eye, Sensitivity To Light, Blurred Vision, Eye Discomfort,
Warnings
Kidney Safe If Prescribed
Dosage adjustment is not required as at low concentration, it does not produce any systemic effects.
Alcohol Safe
It is safe to consume alcohol and Cyclopentolate as there is no drug interaction between them.
Pregnancy Limited Data
The safety of Cyclopentolate in human pregnancy is not established. Therefore, Cyclopentolate should only be used for pregnant women after careful risk/benefit assessment by the doctor.
Driving Not advisable
It may interrupt with visibility during driving as the medication can cause transient blurry vision. Therefore, do not drive whilst you are on this medication.
Liver Limited Data
There is no dose adjustment needed in liver disease as it is a topical medication with low systemic effect.
Lactation Limited Data
It is not known whether Cyclopentolate is excreted into the human breastmilk. It is not advisable to apply topical Cyclopentolate on the chest to avoid accidental contact with the infant.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
