Diacerein
Uses of Diacerein
Diacerein is commonly used in the treatment of osteoarthritis, osteoarthritis of knee and hip joints
How Diacerein Works
Diacerein is a drug which acts on the musculoskeletal system. Diacerein works by inhibiting the interleukin-1β which is also primarily been used for the condition such as osteoarthritis. It is also a derivative of anthraquinone.
Side Effects of Diacerein
Diarrhea, Epigastric pain, Nausea, Vomiting, Yellow coloured urine
Warnings
Kidney Use With Care
Diacerein should be used with caution in patients with kidney disease. Dose adjustment of Diacerein may be needed. Please consult your doctor.
Alcohol Safe
There could be a possible interaction between Diacerein and alcohol. Otherwise, it is fairly safe to consume alcohol while on Diacerein.
Pregnancy Not Safe - High Risk
Diacerein is unsafe to use during pregnancy. Both animal and human studies have shown adverse effects on the fetus. This medicine is strictly prohibited in pregnancy. Use of Diacerein should be started only after pregnancy has been excluded.
Driving Generally Safe
Diacerein usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
Diacerein should be used with care in patients with liver disease. Liver function test monitoring is advisable after 6 months.
Lactation Not Advisable
Diacerein is contraindicated during lactation. Animal studies have shown excretion of Diacerein in milk.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
