Dimenhydrinate
Uses of Dimenhydrinate
Dimenhydrinate is commonly used in the treatment of motion sickness, and vertigo
How Dimenhydrinate Works
Dimenhydrinate is an Antivertigo. Dimenhydrinate works by affecting the effector cells on the GI tract, blood vessels, and respiratory tract by competing with histamine for H1-receptor sites. it also inhibits the chemoreceptor trigger zone and suppresses the vestibular stimulation.
Side Effects of Dimenhydrinate
Dizziness, Drowsiness, Headache, Hallucinations, Confusion, Psychosis, Seizure, Flushed face, Dilated pupils, Ataxia
Warnings
Kidney Safe If Prescribed
Dimenhydrinate can be used in patients with kidney impairment.
Alcohol Not Advisable
Taking Dimenhydrinate with alcohol may increase the sedative effect.
Pregnancy Maybe Safe
Use of Dimenhydrinate is acceptable during pregnancy. Animal reproduction studies do not demonstrate adverse effects on the fetus, and there are no adequate studies in pregnant women. This medication should only be used when there is a clear indication of infection. Please consult your doctor before use.
Driving Not advisable
Do not drive unless you are feeling well. Dimenhydrinate may cause side effects such as drowsiness which could affect the ability to concentrate and drive.
Liver Use With Care
Dimenhydrinate should be used with caution in patients with liver disorder. Dose adjustment of Dimenhydrinate may be needed. Please consult your doctor.
Lactation Not Advisable
Dimenhydrinate is contraindicated during lactation. Animal studies have shown excretion of Dimenhydrinate in milk.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
