Fimasartan
Uses of Fimasartan
Fimasartan is commonly used to treat primary hypertension.
How Fimasartan Works
Fimasartan is an Angiotensin II Antagonists. Blocking the AT1 receptor located on the kidney and adrenal gland, inhibits vasoconstriction and prevents aldosterone formation. Aldosterone increases reabsorption of water and salt by the kidneys, which contributes to increased blood pressure.
Side Effects of Fimasartan
Headache, Dizziness
Warnings
Kidney Use With Care
Fimasartan should be used with caution in patients with varying degrees of kidney disease. Close monitoring of renal function and dose adjustment of Fimasartan may be needed. Please consult your doctor before using it.
Alcohol Not Advisable
Due to lack of data regarding Fimasartan interactions with alcohol, it is unknown whether pharmacokinetics of Fimasartan will be affected when taken simultaneously with alcohol. Please consult your doctor before using it.
Pregnancy Limited Data
Fimasartan may be unsafe to use during pregnancy. There have been human studies showing adverse effects of hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure, oligohydramnios and death. Please consult your doctor before using it.
Driving Generally Safe
Fimasartan may cause side effects such as dizziness and headaches, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.
Liver Limited Data
Fimasartan should be used with caution in patients with liver disease. Dose adjustment of Fimasartan may be needed. Please consult your doctor before using it.
Lactation Limited Data
Fimasartan is excreted into mammal breastmilk but its excretion into human breast milk and the effect on feeding baby is unknown. Please consult your doctor before using it.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
