Finasteride
Uses of Finasteride
Finasteride is commonly used in the treatment of benign prostatic hyperplasia and hair loss.
How Finasteride Works
Finasteride works by inhibiting both tissue and hepatic 5α-reductase. As a result, it prevents the conversion of testosterone to dihydrotestosterone and significantly suppressed serum DHT levels. The reduction of serum DHT then increases hair growth and slows hair loss.
Side Effects of Finasteride
Ejaculation disorder, Decreased libido, Erectile dysfunction, Testicular pain, Gynaecomastia, Rash, Urticaria, Angioedema, Depression, Male breast cancer
Warnings
Kidney Use With Care
There is limited data on the usage of Finasteride in non-dialyzed patients with renal impairment. However, dosage adjustment is not necessary for such patients.
Alcohol Not Advisable
It is not advisable to use Finasteride with alcohol because alcohol may dehydrate and cause difficult urination. The symptoms may also get worse thus, it is recommended to avoid or limit alcohol while taking Finasteride. There are few studies which reported that alcohol can increase the risk of prostate cancer in patients taking Finasteride.
Pregnancy Not Safe - High Risk
When Finasteride is given to a pregnant woman with a male fetus, it will inhibit the development of external genitalia of the fetus. Small amounts of Finasteride have been found from the semen in subjects taking them, though it is unknown whether a male fetus can be affected if his mother is exposed to such semen.
Driving Generally Safe
Finasteride usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
In patients with liver impairment, it is recommended to use Finasteride with caution. There is no data available on the usage of Finasteride in patients with liver disease.
Lactation Limited Data
It remains unknown whether Finasteride is excreted in human breast milk.