Gabapentin

Uses of Gabapentin

Gabapentin is commonly used to treat anxiety disorder, epilepsy, Nerve Pain, and seizures.

How Gabapentin Works

Gabapentin has a similar structure to the GABA neurotransmitter and binds to specific places in the brain that can control the calcium channels presynaptically which controls the rate of release of excitatory neurotransmitters which can help treat anxiety disorder, epilepsy, neuropathic pain, and seizures.

Side Effects of Gabapentin

Drowsiness, Increased risk for infection, Lack of appetite, Dizziness, Loss of balance, Visual disturbances, Acute pancreatitis, Respiratory depression, Anaphylaxis, Angioedema, Back Pain, Suicidal ideation

Warnings

Kidney Use With Care

Gabapentin should be used with caution in patients with kidney disease as dose adjustments may be required. Gabapentin is excreted via the urine so please consult your doctor before starting Gabapentin.

Alcohol Not Advisable

It is unsafe to consume alcohol with Gabapentin. Alcohol may enhance the drowsiness side effect of Gabapentin.

Pregnancy Not Safe

Gabapentin is generally not recommended in pregnant women as animal studies have shown some risks towards the foetus. However, there were no human studies demonstrating it. It should be used only when the benefits outweigh the risks so please consult your doctor before starting Gabapentin.

Driving Not advisable

Do not drive unless you are feeling well. Gabapentin may cause side effects such as dizziness or drowsiness, dizziness or visual disturbances, all of which could affect the ability to concentrate and drive.

Liver Limited Data

Gabapentin is generally safe in patients with liver disease.

Lactation Limited Data

Limited data does show that Gabapentin is excreted in human milk. However, the effect of Gabapentin is not known on human infants. Therefore, please consult your doctor before starting Gabapentin while breastfeeding.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).