Gentamicin

Uses of Gentamicin

Gentamicin is commonly used in the treatment of bacterial infections, skin infections, ear infections and eye infections.

How Gentamicin Works

Gentamicin is an antibiotic under the class of aminoglycosides. It works by disrupting the production of bacterial protein by attaching to the specific subunits of ribosomes, which are the 30s and 50s. This all causes a defected cell membrane in the bacteria.

Side Effects of Gentamicin

Ear toxicity, Allergic rashes, Nausea, Vomiting, Confusion, Tiredness, Liver toxicity, Pain at the injection site, Visual disorders

Warnings

Kidney Use With Care

If Gentamicin is given via Parenteral route, dose adjustment is required for patients with kidney disease. Please consult your doctor to be safe before starting on Gentamicin.

Alcohol Safe

It is safe to consume alcohol with Gentamicin.

Pregnancy Not Safe

Gentamicin has shown evidence that there might be a risk to the human foetus. It is still plausible to be used if the benefits outweigh the risks. Therefore, please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Gentamicin may cause side effects such as brief blurring of vision which could affect the ability to concentrate and drive.

Liver Use With Care

Gentamicin is safe in patients with liver disease.

Lactation Not Advisable

Gentamicin is found in small amounts in breast milk. It is therefore unsafe for breastfeeding as it may risk the infant's development.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).