Glycerin

Uses of Glycerin

Glycerin is commonly used in the treatment of constipation, intestine preparation before any surgery, mouth and throat surgery.

How Glycerin Works

Glycerin works with its osmotic effect with hygroscopic and lubricating properties which causes an increase in plasma osmolality leading to water moving from extravascular space to plasma through osmosis. It also can block sensory cough receptors in the respiratory tract due to its demulcent property.

Side Effects of Glycerin

Arrhythmia, Nausea, Vomiting, Diarrhea, Rash, Abdominal cramp, Dizziness, Headache

Warnings

Kidney Safe If Prescribed

It is safe to be used in patients with kidney problems. Dose adjustment is not required.

Alcohol Safe

It could be safe to consume alcohol with Glycerin, but it is recommended to limit the amount as the interactions are still unknown.

Pregnancy Not Safe

Glycerin is generally not recommended in pregnant women as animal studies have shown some risks towards the foetus. However, there were no human studies demonstrating it. It should be used only when the benefits outweigh the risks so please consult your doctor before starting Glycerin.

Driving Generally Safe

Glycerin usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

It is safe to be used in patients with liver impairment. Dose adjustment is not required.

Lactation Limited Data

Limited data does show that Glycerin is excreted in human milk. However, the effect of Glycerin is not known on human infants. Therefore, please consult your doctor before starting Glycerin while breastfeeding.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).