Hydrochlorothiazide + Losartan
Uses of Hydrochlorothiazide + Losartan
Used for the treatment of hypertension and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy.
How Hydrochlorothiazide + Losartan Works
Hydrochlorothiazide is a thiazide diuretic that reduces the reabsorption of electrolytes, especially sodium and chloride, in the renal tubules, leading to increased excretion of water and electrolytes. Losartan is an angiotensin II receptor antagonist that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II, thereby lowering blood pressure.
Side Effects of Hydrochlorothiazide + Losartan
Common side effects may include dizziness, hypotension, hyperkalemia, and fatigue. Less common but severe side effects can include renal failure, hepatic failure, and angioedema. It's important to seek medical attention if experiencing severe side effects.
Warnings
Kidney Safe If Prescribed
This medication may be safe to use in individuals with kidney issues if prescribed by a healthcare provider. Consultation with a healthcare professional is recommended.
Alcohol Limited Data
Limited data are available regarding the interaction of this combination with alcohol. Caution is advised, and consultation with a healthcare professional is recommended before combining the two.
Pregnancy Safe If Prescribed
This medication may be safe to use during pregnancy if prescribed by a healthcare provider. Consultation with a healthcare professional is recommended to assess potential risks and benefits.
Driving Use With Care
Caution is advised while driving or operating machinery, as this combination may cause dizziness or blurred vision. It is essential to assess individual response before engaging in activities that require alertness.
Liver Limited Data
Limited data are available on the effects of this combination on liver function. Caution is advised, especially in patients with liver conditions. Consultation with a healthcare professional is recommended.
Lactation Limited Data
Limited data are available regarding the safety of this combination during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
