Hydrochlorothiazide + Valsartan

Uses of Hydrochlorothiazide + Valsartan

This medication belongs to the class of ACE inhibitors and ARBs, indicated for the treatment of hypertension.

How Hydrochlorothiazide + Valsartan Works

Hydrochlorothiazide works by decreasing the reabsorption of electrolytes, leading to increased urine production, thus lowering blood pressure. Valsartan blocks the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby relaxing and widening the blood vessels. This combined action helps to lower blood pressure.

Side Effects of Hydrochlorothiazide + Valsartan

Common side effects may include dizziness, headache, fatigue, and hypotension. Less common but serious side effects can include kidney dysfunction, hyperkalemia, and angioedema. Consult a healthcare professional if any severe side effects occur.

Warnings

Kidney Limited Data

Limited data are available regarding the impact of this medication on kidney function. Consultation with a healthcare professional is recommended for individuals with kidney issues.

Alcohol Limited Data

Limited data are available regarding the interaction of this medication with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.

Pregnancy Not Safe - High Risk

This medication is not considered safe during pregnancy due to a high risk of fetal harm. Consultation with a healthcare provider is necessary to evaluate potential risks and benefits.

Driving Use With Care

Caution is advised while driving or operating machinery, as this medication may cause dizziness or drowsiness. It is essential to assess individual response before engaging in activities that require alertness.

Liver Limited Data

Limited data are available on the effects of this medication on liver function. Consultation with a healthcare professional is recommended.

Lactation Limited Data

Limited data are available regarding the safety of this medication during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).