Hydrocortisone

Uses of Hydrocortisone

Hydrocortisone is commonly used in the treatment of arthritis, cancer, eye disorders, nephrotic syndrome, oral lichen planus, rheumatic disorder, severe allergic reactions, and skin disorders

How Hydrocortisone Works

Hydrocortisone is a corticosteroid which exerts anti-inflammatory and immunosuppressive effects. It can inhibit the polymorphonuclear leukocytes from migrating and reversing the increased capillary permeability. It also can be used as hormonal replacement therapy in adrenocortical insufficiency.

Side Effects of Hydrocortisone

Muscle wasting, Osteoporosis, Weakness, Headache, Depression, Obesity, Psychosis, Menstrual irregularities, Infection, Growth retardation in children

Warnings

Kidney Use With Care

Hydrocortisone can be used in patients with kidney impairment. However it may in certain cases cause fluid retention.

Alcohol Use With Care

Alcohol may cause gastric irritation and the concomitant consumption of alcohol and Hydrocortisone may wrosen the gastric problems.

Pregnancy Not Safe

Hydrocortisone may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Driving Generally Safe

Hydrocortisone usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

Hydrocortisone should be used with caution in patients with liver disease. Dose adjustment of Hydrocortisone may be needed. Please consult your doctor.

Lactation Limited Data

There is limited data on the usage of Hydrocortisone during breastfeeding. It is found that Hydrocortisone is excreted in very little quantities in breast milk and not adequate to cause harmful effects. However, it is advisable to practice caution while taking Hydrocortisone during breastfeeding.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).