Mebeverine
Uses of Mebeverine
Mebeverine is commonly used to treat Irritable Bowel Syndrome
How Mebeverine Works
Mebeverine is an antispasmodic agent for the GI smooth muscle. Its various mechanisms of actions are a decrease in ion channel permeability, blockade of norepinephrine reuptake, a local anaesthetic effect, changes in water absorption and weak anti-muscarinergic and phosphodiesterase inhibitory effect.
Side Effects of Mebeverine
Dizziness, Headache, Constipation, Insomnia, Loss of appetite, Decreased heart rate, Hypersensitivity reaction
Warnings
Kidney Use With Care
Mebeverine usage on a patient with kidney disease has not been studied. Dose adjustment of Mebeverine may be needed. Please consult your doctor before using it.
Alcohol Safe
It is safe to consume alcohol with Mebeverine. There's no known drug interactions between them. However, please consult your doctor before using it.
Pregnancy Limited Data
Both animal studies and human studies regarding adverse effects of Mebeverine on the fetus are inconclusive. Please consult your doctor before using it.
Driving Generally Safe
Mebeverine cause minimal to no side effects which could affect your ability to concentrate and drive. Do not drive unless feeling well.
Liver Limited Data
Mebeverine usage on a patient with liver disease has not been studied. Dose adjustment of Mebeverine may be needed. Please consult your doctor before using it.
Lactation Limited Data
It is unknown whether Mebeverine is excreted into breast milk or its potential adverse effect on the feeding baby. Please consult your doctor before using it.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
