Mesalazine
Uses of Mesalazine
Mesalazine/Mesalamine is commonly used to treat Crohn's Disease, Ulcerative Colitis
How Mesalazine Works
Mesalazine/Mesalamine is believed to work by inhibiting the chemicals prostaglandin and leukotriene synthesis in the bowel lining
Side Effects of Mesalazine
Headache, Dizziness, Nausea, Abdominal pain, Anaemia, Skin rash, Balding of the head, Muscle pain, Joint pain
Warnings
Kidney High Risk
Dosage adjustment is needed for patients with mild to moderate renal impairment and is contraindicated for patients with severe renal impairment.
Alcohol Safe
There is no clear contraindication on the consumption of alcohol when taking Mesalazine.
Pregnancy Maybe Safe
Mesalazine has been shown in animal studies to not cause any harm or reproductive toxicity. Human pregnancy data also suggest similar safety profile even though Mesalazine crosses the placenta. It is therefore should be used with caution during pregnancy.
Driving Not advisable
It is not advisable to drive when under Mesalazine treatment due to its potential side effects such as headache and dizziness which can affect the ability to concentrate and drive.
Liver Safe If Prescribed
Dosage adjustment may be needed for patients with mild to moderate hepatic impairment and is contraindicated for patients with severe hepatic impairment.
Lactation Safe If Prescribed
The metabolites of Mesalazine has been detected in human breastmilk and thus it should be used with caution during breastfeeding.