Methimazole
Uses of Methimazole
Methimazole is commonly used to treat Graves Disease, Hyperthyroidism, Toxic Nodular Goitre
How Methimazole Works
Methimazole inhibits the synthesis of thyroid hormones by blocking the oxidation of iodine ion.
Side Effects of Methimazole
Drowsinees, Headache, Vertigo, Balding of the head, Itchiness, Skin rash, Nausea, Vomiting, Joint pain, Muscle pain
Warnings
Kidney Safe If Prescribed
Methimazole is safe to be used and no need dosage adjustment in patients with renal impairment.
Alcohol Safe
There is no clear contraindication on the consumption of alcohol when taking Methimazole.
Pregnancy Not Safe
Methimazole crosses the placenta and birth defects have been observed with the use of Methimazole. It is, therefore, contraindicated to be used during pregnancy.
Driving Not advisable
It is not advisable to drive when under Methimazole treatment due to its potential side effects such as headache, vertigo and dizziness which can affect the ability to concentrate and drive.
Liver Limited Data
There is no dosage adjustment needed for patients with hepatic impairment but caution should be taken if the patient develops signs of hepatotoxicity.
Lactation Limited Data
The metabolites of Methimazole has been detected in human breastmilk and thus it should be used with caution during breastfeeding with the lowest effective dose and close monitoring.