Mupirocin
Uses of Mupirocin
Mupirocin is commonly used to treat severe bacterial infections.
How Mupirocin Works
Mupirocin works by binding to isoleucyl transfer ribonucleic acid (tRNA)-synthetase and thus inhibiting the synthesis of protein by the bacteria. It is bacteriostatic at minimal inhibitory concentrations and bactericidal at higher concentrations.
Side Effects of Mupirocin
Skin irritation, Rash, Dry skin, Erythema, Cellulitis, Secondary wound infection, Swelling, Urticaria, Nausea, Headache, Burning and tearing of eyes, Dry mouth
Warnings
Kidney Use With Care
Mupirocin should be used with caution in patients with kidney disease. However, dosage adjustment is unnecessary.
Alcohol Safe
It is safe to drink alcohol while using Mupirocin.
Pregnancy Maybe Safe
Animal studies did not demonstrate a risk to the fetus and there are inadequate human studies in pregnant women. Mupirocin should only be used if the benefits outweigh the potential risks to the fetus.
Driving Generally Safe
Mupirocin usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
It is safe to use Mupirocin in patients with liver impairment. Adjustment of dosage is not required.
Lactation Limited Data
It is not known whether Mupirocin is excreted in breast milk, therefore care should be practised if the usage during breastfeeding is indicated.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
