Nebivolol
Uses of Nebivolol
Nebivolol is commonly used in the treatment of angina heart related chest pain, arrhythmias and heart failure.
How Nebivolol Works
Nebivolol is a beta-blocker that is selective for B1 adrenergic receptors which are mostly found in our heart muscles. It acts on these receptors and controls their heart rate and contractility, while also having a dilating effect on our blood vessels by stimulating the release of nitric oxide.
Side Effects of Nebivolol
Headache, Dizziness, Numbness, Low Heart Rate, Low Blood Pressure, Shortness of breath, Constipation, Nausea, Diarrhea, Tiredness
Warnings
Kidney Use With Care
Nebivolol may require dose adjustments for patients with kidney disease so consult your doctor before starting this drug as it is excreted via the kidney.
Alcohol Not Advisable
Intake of Nebivolol and alcohol simultaneously may accentuate the side effects of Nebivolol such as dizziness, headache, fainting and change in the heart rate.
Pregnancy Not Safe
Nebivolol may cause harmful effects on foetus as it will reduce blood supply to the foetus, rendering them growth retardation, abortion, early labour or intrauterine death. Hence it should not be used unless it is clearly necessary.
Driving Generally Safe
Nebivolol usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
The studies done on Nebivolol and patients with liver impairment are limited, therefore it is contraindicated for these patients for now.
Lactation Not Advisable
Nebivolol is found to be excreted in animal's breast milk. Human studies haven't been conclusive yet so it is not recommended for pregnant patients to be on Nebivolol as the effects to infants are not known.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
