Nitroglycerin
Uses of Nitroglycerin
Glyceryl Trinitrate/Nitroglycerin is commonly used in the treatment of Angina, Unstable Angina, Heart Attack, Heart Failure and Anal Fissure.
How Nitroglycerin Works
Glyceryl Trinitrate/Nitroglycerin is able to relax vascular smooth muscle cells. It also reduces the sphincter tone and intra-anal pressure, relieving the pain in patients with anal fissure.
Side Effects of Nitroglycerin
Postural hypotension, Peripheral oedema, Abnormal heart rhythm, Flushing, Dizziness, Headache, Nausea, Vomiting, Weakness, Dry mouth
Warnings
Kidney Use With Care
Dose adjustment is needed in patients with severe kidney impairment. Please consult your doctor.
Alcohol Not Advisable
Alcohol may accentuate the hypotensive effects caused by Nitroglycerin. Thus, it is not advisable to consume alcohol during the treatment with Nitroglycerin.
Pregnancy Not Safe
Animal studies do not show reproductive toxicities but there are limited data on the use of Nitroglycerin in pregnant women. Thus, it is only advisable to be used when benefits to the mother are greater than the risk imposed on the fetus. Please consult your doctor.
Driving Not advisable
Do not drive unless you are feeling well. Nitroglycerin may cause side effects such as dizziness which could affect your ability to concentrate and drive.
Liver Use With Care
Dose adjustment is needed in patients with severe liver impairment. Please consult your doctor.
Lactation Not Advisable
Excretion of Nitroglycerin is unknown in human breast milk and risk to breastfed infants cannot be excluded. Thus, it is only advisable to be used when benefits to the mother are greater than the risk imposed on the fetus. Please consult your doctor.