Phenytoin
Uses of Phenytoin
Phenytoin is commonly used to treat Epilepsy, Epileptic seizures, Seizures,
How Phenytoin Works
Phenytoin works by altering the intake and release of sodium ions across the cell membrane in the motor cortex during seizure thus stabilising the nerve impulses firing during the seizure activity.
Side Effects of Phenytoin
Headache, Tremor, Dizziness, Insomnia, Nausea, Vomiting, Acne, Coarse face, Low blood pressure, Gum tenderness
Warnings
Kidney Use With Care
Dosage adjustment may be needed for patient with renal impairment and close monitoring is advisable.
Alcohol Not Advisable
It is not advisable to consume alcohol when taking Phenytoin due to the former may potentiates the central nervous system side effects and vice versa.
Pregnancy Not Safe
There are numerous reports regarding the adverse effects on the fetal development on mothers using Phenytoin during pregnancy. It is therefore, not advisable to take Phenytoin during pregnancy.
Driving Not advisable
It is not advisable to drive when under Phenytoin treatment due to its potential side effects such as headache and dizziness which can affect the ability to concentrate and drive.
Liver Use With Care
Dosage adjustment may be needed for patient with hepatic impairment as Phenytoin is extensively metabolised by the liver.
Lactation Not Advisable
Phenytoin is excreted in small amount into the human breastmilk and due to its potential toxicity towards the nursing infant, it is not recommended to be used during breastfeeding.