Pimecrolimus
Uses of Pimecrolimus
Pimecrolimus is commonly used to treat Atopic Dermatitis
How Pimecrolimus Works
Pimecrolimus is an immunosuppressant which works by blocking the activation and proliferation of T-cells which in turn prevent the release of inflammatory chemicals and mediators from the mast cells.
Side Effects of Pimecrolimus
Burning sensation, Redness of the skin, Skin infection, Swollen lymph nodes, Headache, Cough, Rhinitis, Upper respiratory tract infection, Fever
Warnings
Kidney Safe If Prescribed
No dosage adjustment is needed for patients with renal impairment as indicated by the manufacturer labelling.
Alcohol Not Advisable
It is not advisable to consume or take alcohol when on Pimecrolimus as the latter may exacerbate the skin side effects of alcohol.
Pregnancy Not Safe
Animal reproductive studies have shown foetal toxicity when only given orally. There is no embryological or fetal toxicity when it is applied to the skin. Pimecrolimus should be used with caution during pregnancy considering the risks and benefits.
Driving Generally Safe
Pimecrolimus is generally safe to be used before driving as the side effects profile does not suggest any disruption on the concentration or ability to drive.
Liver Limited Data
There is no dosage adjustment needed for patients with hepatic impairment according to the manufacturer labelling.
Lactation Limited Data
It is not known whether Pimecrolimus is excreted into human breastmilk or not. Due to its potential toxicity, Pimecrolimus is not advisable to be used during breastfeeding.