Pinaverium Bromide
Uses of Pinaverium Bromide
Pinaverium bromide is commonly used to treat Irritable Bowel Syndrome
How Pinaverium Bromide Works
Pinaverium bromide works by inhibiting the intake of calcium ions by the smooth muscle of the gastrointestinal tract.
Side Effects of Pinaverium Bromide
Stomach pain, Headache, Nausea, Rash, Vertigo, Abdominal distension, Constipation, Diarrhea, Drowsiness
Warnings
Kidney Safe If Prescribed
No dosage adjustment is needed for patients with renal impairment as indicated by the manufacturer labelling as systemic absorption is low.
Alcohol Safe
There is no known contraindication in alcohol consumption while taking Pinaverium Bromide.
Pregnancy Limited Data
Animal reproductive data is insufficient while there is no human pregnancy data available to make a safe conclusion for the use of Pinaverium Bromide during pregnancy. It is thus best avoided unless the benefits outweigh the risks.
Driving Generally Safe
Pinaverium Bromide is generally safe to be used before driving as the side effects profile does not suggest any disruption on the concentration or ability to drive. Do not drive if the side effects of Pinaverium Bromide affect the concentration and ability to drive.
Liver Use With Care
There is no dosage adjustment needed for patients with hepatic impairment according to the manufacturer labelling as systemic absorption is low.
Lactation Not Advisable
It is not advisable to breastfeed when on Pinaverium Bromide treatment according to the manufacturer labelling.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
