Raloxifene
Uses of Raloxifene
Raloxifene is commonly used to treat Osteoporosis, Post Menopausal Osteoporosis
How Raloxifene Works
Raloxifene is a selective oestrogen receptor modulator which is able to prevent bone loss by mimicking the action of endogenous oestrogen in bone tissues.
Side Effects of Raloxifene
Hot flushes, Flu-like syndrome, Leg cramps, Peripheral oedema, Excessive sweating, Joint pain, Gut disturbances, Skin rash, Increased blood pressure, Headache, Mild breast pain, Thromboembolism
Warnings
Kidney Use With Care
Caution use has to be practised in patients with mild to moderate kidney impairment. Raloxifene is contraindicated in patients with severe kidney impairment. Please consult your doctor.
Alcohol Safe
There is no known interaction between alcohol and Raloxifene when consumed concomitantly.
Pregnancy Not Safe - High Risk
Raloxifene is used only in postmenopausal women and it may cause reproductive toxicities when used during pregnancy. Thus, it is contraindicated during pregnancy.
Driving Generally Safe
Raloxifene usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
Raloxifene is contraindicated in patients with liver impairment.
Lactation Not Advisable
Excretion of Raloxifene is unknown in human breast milk. Thus, it is not advisable to be used during breastfeeding as risks to breastfed babies cannot be excluded. Please consult your doctor.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
