Repaglinide
Uses of Repaglinide
Repaglinide is commonly used to treat Type 2 Diabetes Mellitus
How Repaglinide Works
Repaglinide is a short-acting meglitinide which is able to block the ATP-dependent K channels in Beta-cell membranes leading to more production of insulin and lowering of blood glucose.
Side Effects of Repaglinide
Hypoglycaemia, Acute coronary syndrome, Abdominal pain, Diarrhea, Joint pain, Back pain, Headache, Increased risk of infection
Warnings
Kidney Use With Care
Dose adjustment is needed in patients with severe kidney impairment. Please consult your doctor.
Alcohol Not Advisable
Alcohol may accentuate the hypoglycaemic effect caused by Repaglinide. Thus, it is not advisable to consume alcohol with Repaglinide concomitantly.
Pregnancy Not Safe
There are no data on the use of Repaglinide in pregnant women. Thus, it is not advisable to be used during pregnancy.
Driving Generally Safe
Repaglinide usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
Caution use has to be practised in patients with liver impairment as there are no clinical studies conducted in this group of patients. Please consult your doctor.
Lactation Limited Data
There are no data on the use of Repaglinide in breastfeeding women. Thus, it is not advisable to be used during breastfeeding.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
