Risedronate Sodium
Uses of Risedronate Sodium
Risedronate sodium is commonly used to treat Osteoporosis, Osteoporosis In Men, Post Menopausal Osteoporosis, Steroid Induced Osteoporosis and Paget's Disease Of Bone.
How Risedronate Sodium Works
Risedronate sodium is able to reduce the activity of osteoclasts which in turn reduce the bone resorption. This mechanism is able to maintain the bone integrity of patients suffering from osteoporosis and Paget’s disease.
Side Effects of Risedronate Sodium
Joint/Muscle/Bone pain, Back pain, Gut disturbances, Allergic reactions, Skin rash, Liver dysfunction, Eye disorders, Osteonecrosis of the jaw, Atypical femur fractures
Warnings
Kidney Use With Care
No dose adjustment is needed for patients with mild to moderate kidney impairment. However, Risedronate Sodium is contraindicated in patients with severe kidney impairment.
Alcohol Not Advisable
Alcohol may accentuate the gut disturbances caused by Risedronate Sodium. Thus, it is not advisable to consume alcohol with Risedronate Sodium concomitantly.
Pregnancy Not Safe
Animal studies have shown reproductive toxicities but there are limited data on the use of Risedronate Sodium in pregnant women. Thus, it is contraindicated during pregnancy.
Driving Generally Safe
Risedronate Sodium usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
Risedronate Sodium is safe to be used in patients with liver impairment.
Lactation Not Advisable
Excretion of Risedronate Sodium has been found in animal milk but it is unknown in human breastmilk. Thus, Risedronate Sodium is contraindicated during breastfeeding.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
