Tacrolimus Topical
Uses of Tacrolimus Topical
Topical tacrolimus is used to treat mild to extreme atopic dermatitis (eczema) in adults who are inadequately receptive to or intolerance to traditional therapies such as topical corticosteroids. Just 0.03% of Topical tacrolimus is used to treat children (2 years of age and older) who have not responded sufficiently to alternative treatments, such as topical corticosteroids.
How Tacrolimus Topical Works
The active ingredient tacrolimus monohydrate, is an immunomodulating agent. In atopic dermatitis, an extreme reaction of the skin's immune system triggers inflammation of the skin (itchiness, redness, dryness). Protopic® alters the unusual immune response and relieves skin irritation and itching.
Side Effects of Tacrolimus Topical
Redness, Feeling Of Warmth, Pain, Increased Skin Sensitivity, Skin Tingling, Rash, Facial Flushing Or Skin Irritation After Drinking Alcohol Is Also Common, Acne
Warnings
Kidney High Risk
Tacrolimus Topical is not safe to be used in patients with kidney disease. Dose adjustment of Tacrolimus Topical may not be required. Please consult your doctor.
Alcohol Not Advisable
It is unsafe to consume alcohol with Tacrolimus Topical. It may cause a visual and neurological effect if consumed with alcohol.
Pregnancy Not Safe
Tacrolimus Topical may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable even with the risk. Please consult your doctor.
Driving Not advisable
Tacrolimus Topical should not affect alertness or driving ability.
Liver Use With Care
Tacrolimus Topical should be used with caution in patients with liver disease. Dose adjustment of Tacrolimus Topical may be needed. Please consult your doctor.
Lactation Not Advisable
Tacrolimus Topical is probably unsafe to use during lactation as some amount of Tacrolimus Topical is excreted in breast milk. Please consult your doctor.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
