Tamoxifen
Uses of Tamoxifen
Tamoxifen is commonly used in the treatment of Breast Cancer.
How Tamoxifen Works
Tamoxifen is an oestrogen receptor inhibitor which is able to prevent the binding of oestrogen onto the oestrogen receptors on the breast tumour. It can also prevent DNA synthesis in cancer cells which in turn halt the progression of breast cancer.
Side Effects of Tamoxifen
Hot flushes, Gut disturbances, Fluid retention, Nausea, Vaginal bleeding or discharge, Skin rash, Alopecia, Headache, Thromboembolism event, Menstruation suppression, Liver enzyme dysfunction
Warnings
Kidney Safe If Prescribed
Tamoxifen is safe to be used in patients with kidney impairment.
Alcohol Not Advisable
There is no known interaction between alcohol and Tamoxifen when used concomitantly. However, alcohol may accentuate the hot flushes or dizziness caused by Tamoxifen. Thus, it is not advisable to consume alcohol if the patient is experiencing side effects from Tamoxifen. Please consult your doctor.
Pregnancy Not Safe
Human studies have shown reports of spontaneous abortions, birth defects and foetal deaths from the use of Tamoxifen during pregnancy. Thus, it is not advisable to be used during pregnancy. Please consult your doctor.
Driving Generally Safe
Tamoxifen usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
Caution use has to be practised in patients with liver impairment as Tamoxifen may cause liver enzyme dysfunction. Please consult your doctor.
Lactation Not Advisable
Excretion of Tamoxifen is not known in human breast milk. Thus, it is not advisable to be used during breastfeeding. Please consult your doctor.