Terbutaline
Uses of Terbutaline
Terbutaline is commonly used in the treatment of Asthma and Chronic Obstructive Pulmonary Disease (COPD).
How Terbutaline Works
Terbutaline is a beta-adrenergic receptor blocker. Terbutaline stimulates the enzyme that catalyses the production of cyclic-3’, 5’-adenosine monophosphate (cAMP). As a result, there is a relaxation of bronchial smooth muscle. On the other hand, terbutaline also inhibits the release of mediators of immediate hypersensitivity from mast cells which in turn reducing the symptoms of asthma.
Side Effects of Terbutaline
Tachycardia, Tremors, Anxiety, Palpitation, Dizziness, Headache, Nausea and vomiting, Fatigue, Sweating, Chest discomfort, Muscle cramps
Warnings
Kidney Safe If Prescribed
No dosage adjustments needed.
Alcohol Not Advisable
It is unsafe to consume alcohol with Terbutaline. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Pregnancy Not Safe
Terbutaline
Driving Generally Safe
Terbutaline usually does not affect ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
No dosage adjustments needed.
Lactation Limited Data
It is secreted into breast milk but it merely exert any effects on newborn. However, there are cases of transient hypoglycemia reported in preterm infants. Please consult your doctor for more details.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
