Trimetazidine
Uses of Trimetazidine
Trimetazidine is commonly used to treat Angina Heart Related Chest Pain, Heart Attack, and Heart Failure.
How Trimetazidine Works
Trimetazidine is an anti-anginal drug. Trimetazidine is able to inhibit B-oxidation of free fatty acid which in turn lower the oxygen demand for the heart. It modulates cardiac metabolism without changing the hemodynamic functions, thus represents an exquisite complementary potential to the regular angina treatment. It ensures the ionic pumps and transmembrane sodium-potassium flow are properly functioning by preventing the reduction of intracellular ATP levels.
Side Effects of Trimetazidine
Dizziness, Headache, Abdominal pain, Diarrhea , Nausea and vomiting, Rash, Palpitation, Postural hypotension
Warnings
Kidney Use With Care
Trimetazidine should be used with caution in patients with moderate and should not be used in severe kidney disease. Please consult your doctor.
Alcohol Not Advisable
It is not appropriate for you to take Trimetazidine with alcohol intake because it may worsen the side effects of Trimetazidine such as dizziness, headache, nausea, and palpitations.
Pregnancy Not Safe
Trimetazidine may be unsafe to use during pregnancy. Animal studies have shown adverse reactions on the fetus, however, there are limited human studies. The benefits from use in pregnant mothers may be tolerable despite the risk. Please consult your doctor.
Driving Not advisable
Do not drive unless you are feeling well. Trimetazidine may cause side effects such as dizziness, headaches, nausea or palpitations, all of which could affect your ability to concentrate and drive.
Liver Limited Data
Trimetazidine should be used with caution in patients with liver disease due to its hepatic metabolism. Dose adjustment of Trimetazidine may be needed. Please consult your doctor.
Lactation Limited Data
Trimetazidine is probably unsafe to use during lactation. Limited human data suggests that Trimetazidine should not be taken for the breastfeeding mothers unless necessary.