Adapalene + Benzoyl Peroxide

Uses of Adapalene + Benzoyl Peroxide

The combination of Adapalene and Benzoyl Peroxide belongs to the class of topical retinoids and antimicrobial agents, and it is indicated for the treatment of acne vulgaris.

How Adapalene + Benzoyl Peroxide Works

Adapalene in combination with Benzoyl Peroxide acts by reducing inflammation, normalizing skin cell turnover, and preventing the formation of acne lesions. Adapalene is a retinoid that promotes cell turnover, while Benzoyl Peroxide has antimicrobial properties, collectively addressing different aspects of acne pathogenesis

Side Effects of Adapalene + Benzoyl Peroxide

Skin dryness, redness, and peeling at the application site. Occasionally, individuals may experience a temporary increase in acne lesions during the initial stages of treatment.

Warnings

Kidney Safe If Prescribed

Adapalene + Benzoyl Peroxide is not used for internal consumption and the amount absorbed into the circulatory system also is negligible to cause any effect even though it is excreted by the urine. It is, therefore, safe to be used even in a patient with renal impairment.

Alcohol Safe

As Adapalene + Benzoyl Peroxide is used topically, the risk of interacting with alcohol consumed is nil. It is therefore to consume alcohol while applying Adapalene + Benzoyl Peroxide.

Pregnancy Not Safe

Because we have very little information about the effects during pregnancy and there's a chance that only a small amount of the medication could pass through the skin, it's recommended not to use Adapalene + Benzoyl Peroxide when pregnant. If pregnancy occurs unexpectedly, stop using the treatment.

Driving Generally Safe

Adapalene + Benzoyl Peroxide is not known to affect the ability to drive or concentrate thus it is safe to be used before driving.

Liver Limited Data

Adapalene + Benzoyl Peroxide is not metabolised by the liver and with only little amount absorbed through the skin into the circulatory system, Adapalene + Benzoyl Peroxide does not cause any harm to the liver. Dose adjustment is not needed in hepatic impaired people.

Lactation Limited Data

Adapalene + Benzoyl Peroxide is probably safe to use during lactation, however, avoid application to the chest to prevent contact exposure of the infant. No human data suggests that Adapalene + Benzoyl Peroxide does not represent a significant risk to the baby.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).

  • Products

    Available medicines with Adapalene + Benzoyl Peroxide
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