Alendronic Acid + Calciferol

Uses of Alendronic Acid + Calciferol

The combination of Alendronic Acid and Calciferol belongs to the class of bisphosphonates and vitamin D analogs, and it is indicated for the treatment of osteoporosis in postmenopausal women.

How Alendronic Acid + Calciferol Works

Alendronic Acid, a bisphosphonate, inhibits bone resorption by binding to hydroxyapatite crystals in bone, thereby reducing bone turnover. Calciferol, a form of vitamin D, aids in calcium absorption, promoting bone mineralization and supporting overall bone health. Together, they address osteoporosis by enhancing bone density and strength.

Side Effects of Alendronic Acid + Calciferol

Gastrointestinal irritation, Heartburn, Nausea, and Musculoskeletal pain.

Warnings

Kidney Safe If Prescribed

Do not require dose adjustment for patients with a glomerular filtration rate (GFR) greater than 35 ml/min. However, it is not recommended for patients with impaired renal function if the GFR is less than 35 ml/min, as there is no data on this.

Alcohol Safe

Alendronic Acid + Calciferol has no interaction with alcohol.

Pregnancy Not Safe

There are no adequate data from the use of Alendronic Acid + Calciferol in pregnant women. Animal studies have shown reproductive toxicity which caused dystocia related to hypocalcemia in rats. Alendronic Acid + Calciferol should not be used during pregnancy.

Driving Generally Safe

Alendronic Acid + Calciferol usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Safe If Prescribed

No dose adjustment is necessary.

Lactation Limited Data

It is not known whether Alendronic Acid + Calciferol/Metabolites are excreted in human milk. A risk to the newborns/infants cannot be excluded. Alendronic Acid + Calciferol not be used during breast-feeding.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).

  • Products

    Available medicines with Alendronic Acid + Calciferol
  •