Alexitol Sodium

Uses of Alexitol Sodium

Alexitol Sodium is commonly used to treat Acidity, Heartburn, Indigestion and Peptic Ulcer Disease

How Alexitol Sodium Works

Alendronic acid is a bisphosphonate which is able to inhibit the activity of Farnesyl Pyrophosphate Synthetase, an enzyme which can increase the activity of osteoclast. Osteoclast is a protein which is responsible for breaking down and resorption of the bone, thus maintaining the bone integrity.

Side Effects of Alexitol Sodium

Abdominal pain, Dyspepsia, Diarrhea, Constipation, Oesophagitis, Oesophageal erosion/ulceration, Oesophageal stricture, Peptic ulceration, Osteonecrosis of the jaw, Bone/Joint/Muscle pain, Femoral fracture, Hypocalcemia, Steven Johnson syndrome, Toxic epidermal necrolysis

Warnings

Kidney Use With Care

Alexitol Sodium may be used in patients with mild to moderate renal impairment. Dosage adjustment may be needed if concentration of aluminium in the blood started to rise. For severe renal impairment, dose adjustment may be needed.

Alcohol Safe

It is not known whether Alexitol Sodium interacts with alcohol or not. It is therefore safe to consume together with alcohol or before/after taking alcohol.

Pregnancy Limited Data

Safety from animal nor human study has not been established. It is therefore not known whether Alexitol Sodium is safe during pregnancy or not although data of other types of antacids suggest other form of antacids with similar actions are safe during pregnancy. Doctor's advice and precaution should be taken if Alexitol Sodium is to be prescribed.

Driving Generally Safe

Alexitol Sodium usually does not affect the ability to drive. Do not drive unless you are feeling well..

Liver Safe If Prescribed

Alexitol Sodium is not metabolised by the liver hence is safe to be used even in liver impairment.

Lactation Limited Data

Alexitol Sodium is not known to be excreted into human breastmilk or not. It is therefore best to change to other form of antacids or hyperacidity reliever with known safety profile during breastfeeding.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).