Alprazolam

Uses of Alprazolam

Alprazolam is commonly used in the treatment of alcohol withdrawal, anxiety, epilepsy, insomnia, muscle spasm, and short term anxiety. It is also used for conscious sedation during diagnostic or therapeutic procedures, as an anaesthesia, and as a sedative.

How Alprazolam Works

Alprazolam is a benzodiazepine which is able to bind to the postsynaptic GABA neuron in the body, preventing nerve impulses from overfiring and calming the person. Hence, it is also used for sedative purposes or sedation during diagnostic or therapeutic procedures.

Side Effects of Alprazolam

Dizziness, Drowsiness, Imbalance, Fatigue, Decreased sex drive, Weight gain/loss, Constipation, Nausea, Sexual Dysfunction, Skin Rashes

Warnings

Kidney Use With Care

Alprazolam should be used with caution in patients with kidney disease. Dose adjustment of Alprazolam may be needed. Please consult your doctor.

Alcohol Not Advisable

It is unsafe to consume alcohol with Alprazolam. Taking Alprazolam with alcohol may have additive effects in increasing the central nervous system depressing effect thus lowering consciousness.

Pregnancy Not Safe

Alprazolam may still be used in pregnancy but with positive evidence of human foetal risk. Hence, should be considered only if no other drugs are effective and the benefits outweigh the risk. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Alprazolam may cause side effects such as dizziness, impaired concentration or tiredness, all of which could affect ability to concentrate and drive.

Liver Use With Care

Alprazolam should be used with caution in patients with liver disease. Dose adjustment of Alprazolam may be needed. Please consult your doctor. Patients with severe liver impairment are contraindicated from taking Alprazolam

Lactation Not Advisable

Alprazolam is excreted in small amounts in the breast milk. Hence, it is not recommended for the patient to be on Alprazolam while breast-feeding.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).