Anastrozole
Uses of Anastrozole
Anastrozole is commonly used to treat Breast Cancer
How Anastrozole Works
Anastrozole is an aromatase inhibitor which prevents the oestradiol precursor to estrone and testosterone thus reducing the oestradiol concentration.
Side Effects of Anastrozole
Hot flushes, Dizziness, Headache, Drowsiness, Nausea, Vomiting, Vaginal dryness, Hair thinning, Limb swelling
Warnings
Kidney Use With Care
Anastrozole concentration does not increase even in patients with severe renal impairment. Caution however, should be exercised in patients with renal impairment since Anastrozole is excreted through urine.
Alcohol Safe
Anastrozole is safe to be consumed with alcohol. No clinical data suggest harmful effect consuming both together.
Pregnancy Not Safe - High Risk
Anastrozole is contraindicated during pregnancy as shown in animal studies where fetal toxicity has been demonstrated.
Driving Not advisable
It is not advisable to take Anastrozole before driving due to potential side effects such as drowsiness and headache which can affect concentration of driving.
Liver Use With Care
Anastrozole concentration can be increased in people with hepatic impairment. Dose adjustment and precautionary measures should be taken for people with hepatic impairment.
Lactation Not Advisable
Anastrozole is contraindicated during lactation period as it has serious potential side effects on the breastfed infant.