Azelastine
Uses of Azelastine
Azelastine is commonly used to treat Allergic Eye Disease, Nasal Allergy Symptoms, Sneezing And Runny Nose Due To Allergies
How Azelastine Works
Azelastine selectively blocks H1-receptors on effector cells, inhibiting the release of histamine involved in the allergic response. It also inhibits the accumulation of other inflammatory mediators.
Side Effects of Azelastine
Mild and transient irritation of the eye Bitter taste Allergic reaction
Warnings
Kidney Safe If Prescribed
Dose adjustment of Azelastine is not needed in patients with renal impairment.
Alcohol Not Advisable
It is unsafe to consume alcohol with Azelastine. Taking Azelastine with alcohol may reduce CNS function and alertness.
Pregnancy Not Safe
Azelastine may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus such as foetal death, growth retardation, skeletal malformation. However, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Driving Generally Safe
Azelastine may cause side effects such as mild and transient irritation. It is unlikely to affect vision to any greater extent. Patient should be advised to wait until the symptom clears before driving.
Liver Use With Care
Dose adjustment of Azelastine is not needed in patients with liver impairment.
Lactation Not Advisable
Azelastine is not safe to be used during lactation as it is excreted into milk in low quantities.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
