Benserazide

Uses of Benserazide

Benserazide is commonly used together with levodopa in the treatment of Parkinson's Disease.

How Benserazide Works

Benserazide is an antiparkinsonian drug that is used together with levodopa in people with Parkinson’s disease. It is a peripheral decarboxylase inhibitor which works by inhibiting the peripheral conversion of levodopa to dopamine, thus increasing the concentration of levodopa to the brain.

Side Effects of Benserazide

Nausea, Vomiting, Anorexia, Diarrhea, Taste disturbances, Cardiac arrhythmias, Orthostatic hypotension, Anxiety, Drowsiness, Depression, Agitation, Insomnia

Warnings

Kidney Use With Care

Benserazide should be used with caution in patients with kidney disease. Dose adjustment of Benserazide may be needed. It is contraindicated in decompensated renal failure. Please consult your doctor.

Alcohol Not Advisable

Consuming alcohol with Benserazide may further lead to side effects such as drowsiness, dizziness, nausea, vomiting and abnormal involuntary movements.

Pregnancy Not Safe

Benserazide and Benserazide has been shown toxicity towards animal fetus study but limited data on pregnant human studies suggest no risk shown. Please consult your doctor before consuming Benserazid and Benserazide during pregnancy.

Driving Not advisable

Do not drive unless you are feeling well. Benserazide may cause side effects such as sleepiness or decreased alertness, all of which could affect the ability to concentrate and drive.

Liver Limited Data

Benserazide should be used with caution in patients with liver disease. Dose adjustment of Benserazide may be needed. Please consult your doctor.

Lactation Limited Data

Benserazide and Benserazide has shown no toxicity in human data of women who are breastfeeding. Precaution should be taken with doctor's advice regarding the use of Benserazide and Benserazide during breastfeeding.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).