Betamethasone
Uses of Betamethasone
Betamethasone is used for the treatment of allergic conditions, asthma, cancer, eye disorders, nephrotic syndrome, oral lichen planus, rheumatic disorder, severe allergic reactions, and skin disorder
How Betamethasone Works
Betamethasone is a corticosteroid which has anti-inflammatory property. It binds to glucocorticoid receptors and reduces the formation, activity, and release of prostaglandins, leukotrienes, and other inflammatory mediators.
Side Effects of Betamethasone
Cushingoid facies, Hirsutism, Weight gain, Increased appetite, hyperhidrosis, Opportunistic infection, osteoporosis, Proximal myopathy, Sodium and water retention, Menstrual irregularity
Warnings
Kidney Use With Care
The effect of Betamethasone on the kidney is not known. However, it is safer to use with caution and consult a doctor before using this medication.
Alcohol Not Advisable
Corticosteroids may cause dry skin. Drinking alcohol may aggravate its side effects.
Pregnancy Not Safe
There is evidence of teratogenicity in animal studies. However, there is no evidence in human studies
Driving Generally Safe
Betamethasone usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
Long term usage of Betamethasone may cause liver damage such as hepatic enlargement and steatosis. It also may exacerbate nonalcoholic steatohepatitis chronic viral hepatitis
Lactation Limited Data
Betamethasone is probably safe to use during lactation. Limited human data and animal studies suggest that Betamethasone does not represent a significant risk to nursing infants. However, Betamethasone needs to be taken with caution.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
