Carbenoxolone
Uses of Carbenoxolone
Carbenoxolone is commonly used to treat Gastroesophageal Reflux Disease Acid Reflux, Mouth Ulcers, Peptic Ulcer Disease
How Carbenoxolone Works
Carbenoxolone is a synthetic derivative of glycyrrhizinic acid. It works by protecting the mucosal barrier from acid-pepsin attachment and enhancing mucin production thereby protecting the stomach lining.
Side Effects of Carbenoxolone
Sodium and water retention Hypokalemia
Warnings
Kidney Use With Care
Carbenoxolone should be used with caution in patients with severe renal disease. Dose adjustment of Carbenoxolone may be needed. Please consult your doctor.
Alcohol Limited Data
It is not advisable to consume alcohol with Carbenoxolone as there is no information about the interaction between them.
Pregnancy Not Safe - High Risk
Carbenoxolone is not safe to use during pregnancy. Animal studies and human studies have shown adverse effects on the fetus.
Driving Limited Data
There is no data regarding the influence caused by Carbenoxolone on driving. Thus, it is not recommended to drive whilst on Carbenoxolone.
Liver Limited Data
Carbenoxolone should be used with caution in patients with liver disease as dosage adjustment may be required. Please consult your doctor.
Lactation Limited Data
There is no information about the presence of Carbenoxolone in human milk. Hence, it is not recommended to take Carbenoxolone whilst breastfeeding.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
