Cefuroxime

Uses of Cefuroxime

Cefuroxime is commonly used in the treatment of Urinary Tract Infections Utis, Meningococcal Disease, Gonorrhea, Lyme Disease, Respiratory infections

How Cefuroxime Works

Cefuroxime inhibits bacterial cell wall synthesis. It works by binding to penicillin-binding proteins which results in inhibition of the final step of peptidoglycan synthesis in bacterial cell wall. Therefore, inhibiting cell wall synthesis and arresting the assembly of cell wall leading to cell death.

Side Effects of Cefuroxime

Headache, Dizziness, Elevated liver enzymes, Diarrhea, Nausea, Candida overgrowth, Abdominal pain, Elevated eosinophil

Warnings

Kidney Use With Care

Cefuroxime should be used with caution in patients with kidney disease. Dose titration of Cefuroxime may be needed as it is excreted by the kidney.

Alcohol Safe

It is safe to consume alcohol with Cefuroxime as there is no known drug interaction.

Pregnancy Maybe Safe

Cefuroxime should only be used if benefits outweigh the risks. Animal studies do not show any adverse effects on the fetus, however, there are limited human studies. Please consult your doctor.

Driving Limited Data

There is no information regarding the safety of Cefuroxime taken whilst driving. Nevertheless, it may cause side effects such as dizziness which could affect your ability to concentrate and drive.

Liver Safe If Prescribed

Cefuroxime is safe to be used in patients with liver impairment as it is predominantly being eliminated by the kidney.

Lactation Safe If Prescribed

Cefuroxime is probably safe to use during lactation. It is excreted in small quantities in breast milk. Adverse effects are not expected however the possibility of Diarrhea and fungal infection cannot be excluded. It can be used if the benefits outweigh the risks.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).