Cimetidine
Uses of Cimetidine
Cimetidine is commonly used in the treatment of Gastroesophageal Reflux Disease, Acid Reflux and Peptic Ulcer Disease.
How Cimetidine Works
Cimetidine is an antacid. It competitively inhibits H2-receptors of the gastric parietal cells and reduces the gastric acid secretion, gastric volume and hydrogen ion concentration which are all increased in Gastroesophageal Reflux Disease and Peptic Ulcer Disease.
Side Effects of Cimetidine
Diarrhea, Headache, Dizziness, Tiredness, Tachycardia, Myalgia, Arthralgia, Rashes, Confusion, Hypersensitivity reactions
Warnings
Kidney Use With Care
Cimetidine should be used with caution in patients with kidney disease. Dose adjustment of Cimetidine may be needed. Please consult your doctor.
Alcohol Not Advisable
It is unsafe to consume alcohol with Cimetidine. Taking Cimetidine with alcohol may enhance gastric mucosal irritation.
Pregnancy Maybe Safe
Cimetidine may be safe to use during pregnancy. Animal reproduction studies have not shown any risk to the fetus. However, Cimetidine does cross the placental barrier and hence must be used with precaution. Please consult your doctor.
Driving Generally Safe
Cimetidine usually does not affect the ability to drive. Do not drive unless you are well.
Liver Limited Data
Cimetidine should be used with caution in patients with liver disease. Dose adjustment of Cimetidine may be needed. Please consult your doctor.
Lactation Limited Data
Cimetidine is probably safe to use during lactation. Cimetidine is excreted in breast milk. Limited human data suggests that Cimetidine does not represent a significant risk to the baby. Please consult your doctor.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
