Dapagliflozin + Metformin

Uses of Dapagliflozin + Metformin

This medication is a combination of dapagliflozin and metformin, belonging to the class of biguanides, indicated for the management of type 2 diabetes mellitus.

How Dapagliflozin + Metformin Works

Dapagliflozin works by inhibiting SGLT2, which reduces renal glucose reabsorption, leading to increased urinary glucose excretion. Metformin decreases hepatic glucose production and improves insulin sensitivity in peripheral tissues.

Side Effects of Dapagliflozin + Metformin

Common side effects may include nausea, diarrhea, abdominal discomfort, and urinary tract infections.

Warnings

Kidney Limited Data

Limited data are available regarding the impact of this medication on kidney function. Consultation with a healthcare professional is recommended for individuals with kidney issues.

Alcohol Limited Data

Limited data are available regarding the interaction of this medication with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.

Pregnancy Limited Data

There is limited data on the safety of this medication during pregnancy. Consultation with a healthcare provider is recommended to assess potential risks and benefits.

Driving Generally Safe.

This medication is generally safe for driving, but caution is advised as it may cause dizziness or lightheadedness in some individuals. It is essential to assess individual response before engaging in activities that require alertness.

Liver Limited Data

Limited data are available on the effects of this medication on liver function. Caution is advised, especially for individuals with liver conditions. Consultation with a healthcare professional is recommended.

Lactation Limited Data

Limited data are available regarding the safety of this medication during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).