Darifenacin
Uses of Darifenacin
Darifenacin is commonly used to treat Overactive Bladder Syndrome
How Darifenacin Works
Darifenacin inhibits specifically muscarinic M3 receptor which functions to control urinary bladder contraction. Therefore, it can overcome symptoms of urge incontinence and/or increased urinary frequency and urgency in overactive bladder syndrome.
Side Effects of Darifenacin
Headache, Dry eye, Nasal dryness, Constipation, Dry mouth, Abdominal pain, Nausea, Dyspepsia, Skin dryness/flushing.
Warnings
Kidney Use With Care
Dose adjustment of Darifenacin is not needed in patients with impaired renal function. However, caution should be exercised when managing patients with underlying renal impairment. Please consult your doctor before using it.
Alcohol Safe
It is safe to consume alcohol with Darifenacin as there are no drug/alcohol interactions.
Pregnancy Not Safe
Animal studies have shown that male or female infertility is not affected in rats and cats. But, there are limited human studies. The benefits may outweigh risks from use in pregnant women. Please consult your doctor before using it.
Driving Not advisable
Darifenacin may cause side effects such as headaches and blurred vision which could affect concentration and your ability to drive. Only drive if you are well.
Liver Limited Data
Darifenacin should be used with caution in patients with liver disease of varying degree. No dose adjustment is needed in mild liver impairment but the dose for in moderate liver impairment is limited to 7.5 mg daily. Darifenacin is absolutely not for severe liver impairment.
Lactation Limited Data
Darifenacin is excreted in the breast milk of rats but its safety profile is limited in human data. Please consult with your doctor whether to stop breast- feeding or to halt Darifenacin therapy during lactation unless benefits outweigh the risk of Darifenacin.