Diphtheria Toxoid

Uses of Diphtheria Toxoid

Diphtheria Toxoid is commonly used in the prevention of diphtheria

How Diphtheria Toxoid Works

The development of neutralizing antibodies to diphtheria toxin generated from diphtheria toxoid protects against the diphtheria disease. Diphtheria toxoid will stimulate the immune system to produce antibodies against it which will protect the vaccinated person.

Side Effects of Diphtheria Toxoid

Nausea, Vomiting, Diarrhea, Pain, Swelling & erythema at injection site, Fever, Rash, Muscle weakness, Chills, Axillary lymph node swelling

Warnings

Kidney Use With Care

It is recommended to administer the Diphtheria Toxoid vaccine with caution in patients with renal impairment. There is limited data on the safety profile of the vaccine as diphtheria infection is quite rare.

Alcohol Not Advisable

It is not advisable to drink alcohol following administration of Diphtheria Toxoid as there could be possible interactions between both.

Pregnancy Not Safe

Animal studies have demonstrated that Diphtheria Toxoid may cause adverse effects on the fetus and there are inadequate human studies. However, if there is a high risk of exposure to the diphtheria infection, the benefits of administering this vaccine over the potential risk should be assessed. The inactivated vaccine also may not cause any risk to the fetus.

Driving Generally Safe

Diphtheria Toxoid usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

It is recommended to administer the Diphtheria Toxoid vaccine with caution in patients with liver impairment. There is limited data on the safety profile of the vaccine as diphtheria infection is quite rare.

Lactation Limited Data

It remained unknown whether Diphtheria Toxoid is safe to be used during breastfeeding. The decision to administer the vaccine or continue breastfeeding depends on the benefits of vaccine to mother or benefits of breastfeeding to infant.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).