Dipyridamole

Uses of Dipyridamole

Dipyridamole is commonly used to treat Blood Clot Formation After Cardiac Valve Replacement as well as Prevention Of Heart Attack And Stroke.

How Dipyridamole Works

Dipyridamole is an oral anticoagulant for preventing blood clot formation. It inhibits adenosine deaminase and phosphodiesterase along the pathway of platelet aggregation. In addition, Dipyridamole has vasodilating properties through accumulation of prostacyclin or PGD2.

Side Effects of Dipyridamole

Angina pectoris, Hypotension, Headache, Dizziness, Diarrhea, Nausea, Vomiting, Rash, Muscle ache, Risk of bleeding

Warnings

Kidney Safe If Prescribed

Renal excretion of Dipyridamole is low and studies have shown no change in its metabolism when used in patients with kidney disease of varying degrees. However, please consult your doctor before using it.

Alcohol Not Advisable

It is not advisable to take alcohol simultaneously with Dipyridamole. Alcohol can potentiate the side effects of headache and dizziness caused by Dipyridamole.

Pregnancy Maybe Safe

Dipyridamole may be unsafe to use during pregnancy. Animal studies have not shown adverse effects on the fetus, however, there are limited human studies. Please consult your doctor before using it as its benefits may outweigh the risk of usage in a pregnant woman.

Driving Not advisable

Dipyridamole may cause side effects of dizziness and headaches all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Liver Limited Data

Dipyridamole should be used with caution in patients with clinically known liver disease. Dose adjustment of Dipyridamole may be needed. Please consult your doctor before using it.

Lactation Limited Data

Dipyridamole is excreted into breast milk. However, its effect on the feeding baby is largely unknown. Hence, the decision to discontinue Dipyridamole or stop breastfeeding is to be done after consulting your doctor.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).