Dulaglutide

Uses of Dulaglutide

Dulaglutide is commonly used to treat Type 2 Diabetes Mellitus with addition of changes to diet and exercise.

How Dulaglutide Works

Dulaglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist.

Side Effects of Dulaglutide

Hypoglycaemia, nausea, diarrhoea, vomiting, abdominal pain, Decreased appetite, dyspepsia, constipation, flatulence, abdominal distention, GERD, eructation, fatigue

Warnings

Kidney Use With Care

Patients with mild, moderate or severe renal impairment might not need dose adjustment. However, use of Dulaglutide in patients with end-stage renal disease is not recommended. Discuss with your doctor regarding this managements.

Alcohol Not Advisable

Alcohol may affect blood glucose levels in patients with diabetes. Generally, it is not advisable to have alcohol with Dulaglutide.

Pregnancy Not Safe

Limited data exist for the use of Dulaglutide in pregnant women. Therefore, Dulaglutide should not be used during pregnancy.

Driving Generally Safe

It is generally safe to drive while on Dulaglutide. However, patients who have reduced or absent awareness of warning signs of hypoglycemia or frequent episodes of hypoglycemia must take precautions while driving. It is best to avoid since hypoglycemia may impair the ability to concentrate and react while driving.

Liver Use With Care

No dose adjustment is required in patients with liver impairment. Caution should still be exercised when using Dulaglutide with liver impairment.

Lactation Not Advisable

Dulaglutide should not be used during breastfeeding

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).