Ezetimibe + Simvastatin

Uses of Ezetimibe + Simvastatin

This medication is indicated for the treatment of high cholesterol levels, specifically to lower LDL cholesterol, also known as "bad" cholesterol, in the blood.

How Ezetimibe + Simvastatin Works

Ezetimibe works by reducing the absorption of cholesterol in the intestine, while simvastatin belongs to the class of drugs known as statins, which work by blocking the enzyme HMG-CoA reductase in the liver, thereby reducing the production of cholesterol.

Side Effects of Ezetimibe + Simvastatin

Common side effects may include headache, muscle pain, diarrhea, and fatigue. Less common but serious side effects can include liver problems, muscle breakdown, and an increased risk of diabetes.

Warnings

Kidney Limited Data

Limited data are available regarding the impact of this medication on kidney function. Consultation with a healthcare professional is recommended for individuals with kidney issues.

Alcohol Limited Data

Limited data are available regarding the interaction of this medication with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.

Pregnancy Not Safe - High Risk

This medication is not safe for use during pregnancy due to the potential risk of harm to the fetus. It carries a high risk of birth defects and other adverse effects. Consultation with a healthcare provider is necessary to discuss alternative treatment options.

Driving Use With Care

Caution is advised while driving or operating machinery, as this medication may cause dizziness or fatigue, which can impair your ability to perform these tasks safely.

Liver High Risk

This medication carries a high risk of liver problems, including liver damage and abnormal liver function tests. Close monitoring of liver function is essential during treatment.

Lactation Limited Data

Limited data are available regarding the safety of this medication during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).