Fentanyl

Uses of Fentanyl

Fentanyl is commonly used to treat Anesthesia, Dry Cough, Moderate To Severe Pain, Opioid Dependence, Severe Chronic Pain

How Fentanyl Works

Fentanyl functions as a potent agonist of opioid receptors in the central nervous system, producing analgesia by altering the perception of and response to pain signals. It primarily acts on mu-opioid receptors, leading to inhibition of neurotransmitter release, resulting in pain relief and sedation.

Side Effects of Fentanyl

Common side effects may include nausea, vomiting, constipation, drowsiness, and respiratory depression. Serious side effects can include slowed heart rate, low blood pressure, and potentially fatal respiratory depression.

Warnings

Kidney Limited Data

Limited data are available regarding the impact of Fentanyl on kidney function. Consultation with a healthcare professional is recommended for individuals with kidney issues.

Alcohol Limited Data

Limited data are available regarding the interaction of Fentanyl with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.

Pregnancy Limited Data

There is limited data on the safety of Fentanyl during pregnancy. Consultation with a healthcare provider is recommended to assess potential risks and benefits.

Driving Use With Care

Caution is advised while driving or operating machinery, as Fentanyl may cause drowsiness or impairment of cognitive and motor functions. Individuals should assess their response to the medication before engaging in activities that require alertness.

Liver Limited Data

Limited data are available on the effects of Fentanyl on liver function. Caution is advised, especially for individuals with liver conditions. Consultation with a healthcare professional is recommended.

Lactation Limited Data

Limited data are available regarding the safety of Fentanyl during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).